Sermorelin and enclomiphene are two therapies commonly used in hormone optimization, but they work in very different ways. Patients often compare these options when addressing symptoms related to low testosterone, energy levels, recovery, or overall hormonal balance. Understanding how each therapy functions is essential when deciding which approach may be more appropriate.

Sermorelin is a peptide that stimulates the body’s natural production of growth hormone by acting on the pituitary gland. It is often considered when the goal is to support recovery, sleep quality, body composition, and overall vitality through growth hormone pathways. Enclomiphene, on the other hand, works by stimulating the body’s own testosterone production through the hypothalamic-pituitary-gonadal axis, making it a commonly considered option for individuals seeking to increase testosterone levels while preserving endogenous function.

This comparison is designed to clearly outline the differences in mechanism of action, intended use, and typical considerations for each therapy. Rather than promoting one option over the other, the goal is to provide objective, educational information that supports informed discussions and individualized treatment planning.

At Equivalence Wellness, treatment decisions are guided by clinical context, laboratory data, symptoms, and long-term health goals. If you are considering sermorelin, enclomiphene, or are unsure which option may be appropriate, our medical team offers personalized consultations to review your options and develop a plan aligned with your needs.